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Search Result

Search Results for " erk 3 "

Targets

ERK

24

Compounds

14

Natural Products

74

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T9141 ERK-IN-3 ASN007 free base ERK
ERK-IN-3 (ASN007 free base) is a potent and orally active inhibitor of ERK. It inhibits ERK1/2 with low single-digit nM IC50 values. It can be used for the research of cancers driven by RAS mutations.
T39453 ERK-IN-3 benzenesulfonate
ERK-IN-3 benzenesulfonate is a potent and orally active inhibitor of ERK . ERK-IN-3 benzenesulfonate inhibits ERK1/2 with low single-digit nM IC 50 values. ERK-IN-3 benzenesulfonate can be used for the research of cancer...
T0860L Mefloquine Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998 Others
Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic l...
T6993 Tauroursodeoxycholate sodium Sodium tauroursodeoxycholate,Tauroursodeoxycholic acid sodium salt,TUDC,Sodium Tauroursodeoxycholate (TUDC) Apoptosis , ERK , Caspase
Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.
T27242 EF24 EF 24,EF-24,3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone ERK , MEK , Caspase
EF24 (3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral ...
T20759 XRP44X XRP-44-X,XRP 44X,XRP-44X,XRP 44 X Ras
XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.
T3636 (E)-SIS3 SIS3,SIS3 HCl TGF-beta/Smad
(E)-SIS3 (SIS3), a selective Smad3 inhibitor, can attenuate TGF-β1-dependent Smad3 phosphorylation and DNA binding. It has no effect on p38 MAPK, Smad2, ERK or PI3K signaling. It also inhibits TGF-β1-induced myofibroblas...
T9428 HM43239 FLT
HM43239 is an orally active and selective FLT3 inhibitor with IC 50 s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. HM43239 directly inhibits the k...
T16998 Tauroursodeoxycholate dihydrate Taurolite dihydrate,TUDCA dihydrate,UR 906 dihydrate ERK , Caspase
Tauroursodeoxycholate dihydrate is an endoplasmic reticulum stress inhibitor. Tauroursodeoxycholate also inhibits ERK. Tauroursodeoxycholate significantly decreases the expression of apoptosis molecules, such as caspase-...
T73039 CYP1B1-IN-3
CYP1B1-IN-3 is a potent, selective inhibitor of CYP1B1, exhibiting IC50 values of 6.6 nM for CYP1B1, 347.3 nM for CYP1A1, and >10000 nM for CYP1A2. It also impedes cell migration and invasion, and inhibits the P-gp, AKT/...
T36584 HNMPA-(AM)3 Tyrosine Kinases
HNMPA-(AM)3 inhibits activation of ERK phosphorylation and stimulation of ecdysteroid production by prothyrotropin (PTTH). Furthermore, HNMPA-(AM)3 had inhibitory effects on ecdysteroid production (IC50=14.2 μM) and insu...
T62784 KRAS inhibitor-18
KRAS inhibitor-18 (compound 3-10) is a potent inhibitor of KRAS G12C (IC50: 4.74 μM). KRAS inhibitor-18 exhibited p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 66.4, 11.1 μM respectively. KRAS inhibitor-18 has...
T62752 KRAS inhibitor-16
KRAS inhibitor-16 (compound 3-11) is a potent inhibitor of KRAS G12C (IC50: 0.457 μM). KRAS inhibitor-16 exhibits p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 3.06, 11.1 μM respectively. KRAS inhibitor-16 has...
T74373 ERK1/2 inhibitor 3
ERK1/2 Inhibitor 3, a potent inhibitor of ERK1/2, plays a crucial role in the signal transduction pathway by targeting the Mitogen-activated protein kinase (MAPK) family, specifically the extracellular signal-regulated k...
T62981 KRAS inhibitor-17
KRAS inhibitor-17 (compound 3-9) is a potent inhibitor of KRAS G12C (IC50: 3.37 μM). KRAS inhibitor-17 exhibits p-ERK inhibition with IC50 = 9.25 μM in MIA PaCA-2 cells and >33.3 μM in A549 cells. KRAS inhibitor-17 has t...
T79808 KRAS G12C inhibitor 61 ERK
KRAS G12C inhibitor 61 (Example 3) demonstrates potent activity by inhibiting phospho-ERK 1/2 in MIA PaCa-2 cells, reflected in an IC50 value of 9 nM. This inhibitor is applicable in the research of pancreatic, colorecta...
T62737 KRAS inhibitor-15
KRAS inhibitor-15 (compound 3-19) is a potent inhibitor of KRAS G12C (IC50: 0.954 μM). KRAS inhibitor-15 exhibits p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 2.03, >33.3 μM, respectively. KRAS inhibitor-15 h...
T63967 Multi-kinase-IN-2
Multi-kinase-IN-2 is an orally active inhibitor of angiokinases. multi-kinase-IN-2 significantly inhibits the activity of angiokinases such as VEGFR-1/2/3, PDGFRα/β, FGFR-1, LYN and c-KIT kinases. -IN-2 significantly att...
T76022 Chemerin-9 (149-157) (TFA)
Chemerin-9 (149-157) TFA is a potent CMKLR1 (chemokine-like receptor 1) agonist with anti-inflammatory properties. It activates phosphorylation of Akt and ERK and induces ROS production, beneficially modulating immune re...
T76536 Pinealon
Pinealon is a 3-amino acid peptide and shows neuroprotective properties. Pinealon prevents reactive oxygenspecies (ROS) accumulation and supressesthe activation of ERK 1/2. Pinealon has the ability to stimulate the funct...
T78871 PLM-101
PLM-101 is an anticancer compound orally active against acute myeloid leukemia by targeting FLT3 and RET. It impedes RET function, promoting autophagic breakdown of FLT3, and suppresses the PI3K and Ras/ERK pathways, con...
T35940 Darinaparsin Dimethylarsinic glutathione,Darinaparsin
Darinaparsin is a dimethylated arsenic linked to glutathione. It is cytotoxic to DU145, LNCaP, and PC3 prostate cancer cells (IC50s = 5-10 &#181M) and patient-derived primary prostate cancer cells (IC50s = 2.5-20 &#181M)...
T71328 Theobromine-d6
Theobromine-d6 is intended for use as an internal standard for the quantification of theobromine by GC- or LC-MS. Theobromine is a methylxanthine alkaloid and derivative of caffeine that has been found in cocoa beans and...
T36679 Rp-cAMPS sodium salt
Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS sodium salt is resistant to hydrolysis b...
Cat No. Product Name Synonyms Targets
T6S0619 Pachymic acid 3-O-Acetyltumulosic acid ERK , Akt
Pachymic acid (3-O-Acetyltumulosic acid) is a natural product, and inhibits Akt and ERK signaling pathways.
TN2354 Methylnissolin 3-Hydroxy-9,10-dimethoxyptercarpan ERK , PDGFR
Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.
T13265 Urolithin B ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...
T2532 Tauroursodeoxycholate Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. Tauroursodeoxycholate is the more hydrophilic form of ursode...
T6S0923 Hypericin Hypericine,Cyclosan Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC
1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL...
TN1880 Lucidenic acid B Lucidenicacid B Apoptosis , Caspase
Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mito...
T6S1740 Nardosinone Others
1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed t...
T5S0890 Oleandrin Neriostene,Folinerin,Foliandrin Apoptosis , ATPase , Potassium Channel , Sodium Channel
1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, ...
T3876 Loureirin B PAI-1 , ERK , Potassium Channel , JNK
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathw...
T3S2344 β,β-Dimethylacrylshikonin Dimethylacrylshikonin,β, β-Dimethylacrylshikonin ERK , HIF/HIF Prolyl-Hydroxylase
1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant...
T6S0525 Farrerol ERK , p38 MAPK , Akt
1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3....
T4S0878 Prunetin Prunusetin ERK , Dehydrogenase , NF-κB
1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit...
T6S1597 Mulberroside A TNF , Tyrosinase , Interleukin
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...
T72152 Eicosapentaenoic Acid sodium Timnodonic acid sodium,EPA sodium
Eicosapentaenoic Acid (EPA) sodium, an orally active omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA), demonstrates a unique ability to demethylate DNA, thereby facilitating the re-expression of the tumor supp...

Natural Products

Pachymic acid
T6S0619
Synonym: 3-O-Acetyltumulosic acid
Target: ERK, Akt
Methylnissolin
TN2354
Synonym: 3-Hydroxy-9,10-dimethoxyptercarpan
Target: ERK, PDGFR
Urolithin B
T13265
Synonym:
Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK
Tauroursodeoxycholate
T2532
Synonym: Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA
Target: Apoptosis, ERK, P450, Caspase, Endogenous Metabolite
Hypericin
T6S0923
Synonym: Hypericine,Cyclosan
Target: Apoptosis, Antiviral, Influenza Virus, Tyrosine Kinases, Antibacterial, PKC
Lucidenic acid B
TN1880
Synonym: Lucidenicacid B
Target: Apoptosis, Caspase
Nardosinone
T6S1740
Synonym:
Target: Others
Oleandrin
T5S0890
Synonym: Neriostene,Folinerin,Foliandrin
Target: Apoptosis, ATPase, Potassium Channel, Sodium Channel
Loureirin B
T3876
Synonym:
Target: PAI-1, ERK, Potassium Channel, JNK
β,β-Dimethylacrylshikonin
T3S2344
Synonym: Dimethylacrylshikonin,β, β-Dimethylacrylshikonin
Target: ERK, HIF/HIF Prolyl-Hydroxylase
Farrerol
T6S0525
Synonym:
Target: ERK, p38 MAPK, Akt
Prunetin
T4S0878
Synonym: Prunusetin
Target: ERK, Dehydrogenase, NF-κB
Mulberroside A
T6S1597
Synonym:
Target: TNF, Tyrosinase, Interleukin
Eicosapentaenoic Acid sodium
T72152
Synonym: Timnodonic acid sodium,EPA sodium
Target:

Recombinant Proteins

Species：
Human (69)
Mouse (3)
Canine (1)
Cynomolgus (1)
Expression System：
HEK293 (47)
Baculovirus-Insect Cells (15)
E. coli (6)
Human Cells (5)
in vitro E. coli expression system (1)
Tag：
His (22)
Tag Free (8)
hFc (7)
His,GST (6)
GST (5)
mFc (5)
C-Fc (4)
C-His-Avi (3)
C-6His (2)
C-Avi (2)
Cat No. Product Name Species Expression System
TMPY-04430 P38 gamma/MAPK12 Protein, Human, Recombinant Human Baculovirus-Insect Cells
ERK3, also known as MAPK12 and p38-gamma, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. ERK3 is highly expressed in skeletal muscle and heart. ERK3 is a serine/t...
TMPY-04429 P38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
ERK3, also known as MAPK12 and p38-gamma, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. ERK3 is highly expressed in skeletal muscle and heart. ERK3 is a serine/t...
TMPY-00784 EphB2 Protein, Human, Recombinant (His & hFc) Human HEK293
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5...
TMPY-04386 EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) Human Baculovirus-Insect Cells
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5...
TMPY-01067 EphB2 Protein, Human, Recombinant (His) Human HEK293
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5...
TMPK-00563 EPHB2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated p...
TMPH-01609 LGI1 Protein, Human, Recombinant (His & Myc) Human E. coli
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regula...
TMPY-04378 MAPKAPK3 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
The MAPKAP kinases are a group of MAP kinase substrates that are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases ...
TMPY-03482 DUSP3 Protein, Human, Recombinant Human Baculovirus-Insect Cells
Vaccinia H1-related phosphatase (VHR) is classified as a dual-specificity phosphatase (DUSP), and the other name is dual-specificity phosphatase 3 (DUSP3). DUSPs are a heterogeneous group of protein phosphatases that can...
TMPY-02127 DUSP3 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Vaccinia H1-related phosphatase (VHR) is classified as a dual-specificity phosphatase (DUSP), and the other name is dual-specificity phosphatase 3 (DUSP3). DUSPs are a heterogeneous group of protein phosphatases that can...
TMPY-00357 HNT/NTM Protein, Human, Recombinant (His) Human HEK293
NTM (Neurotrimin) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylph...
TMPY-06986 FGF-8b Protein, Human, Recombinant Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-04142 RANK/TNFRSF11A Protein, Human, Recombinant (hFc) Human HEK293
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-05748 CD45 Protein, Human, Recombinant (aa 26-577, His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00132 Mesothelin Protein, Human, Recombinant Human HEK293
The megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glyc...
TMPY-05191 CD47 Protein, Human, Recombinant, Biotinylated Human HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-03763 Neuropilin-2 Protein, Human, Recombinant (hFc) Human HEK293
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac...
TMPY-00892 Neuropilin-2 Protein, Human, Recombinant (His) Human HEK293
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac...
TMPY-01020 Periostin/OSF-2 Protein, Human, Recombinant (His) Human HEK293
Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPY-04683 CD47 Protein, Human, Recombinant Human HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-01897 PRSS3 Protein, Human, Recombinant (His) Human HEK293
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on...
TMPY-04374 MST4 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
MST4, also known as mammalian STE2-like protein kinase 4, is a novel member of the germinal center kinase subfamily of human Ste2-like kinases and is closely related to MST3. The 416 amino acid full-length MST4 contains ...
TMPY-04298 CDCP1 Protein, Human, Recombinant (His) Human HEK293
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-00480 NCAM1 Protein, Human, Recombinant (His) Human HEK293
NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobuli...
TMPY-01180 CD86 Protein, Human, Recombinant (His) Human HEK293
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co...
TMPJ-01099 IL-15RA Protein, Human, Recombinant (hFc, Human Cells) Human Human Cells
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bi...
TMPY-04935 CD47 Protein, Human, Recombinant (aa 1-139, His) Human HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-00072 GITR/TNFRSF18 Protein, Human, Recombinant (His) Human HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)...
TMPY-04466 STK40 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
STK40 is localized to both the cytoplasm and the nucleus. It is ubiquitously expressed. Mechanistically, Stk40 interacts with Rcn2, which also activates Erk1/2 to induce ExEn specification in mouse ESCs. Stk40 is able to...
TMPY-04571 ERK2 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus-Insect Cells
MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, diffe...
TMPY-04539 ERK2 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, diffe...
TMPY-04467 NME1 Protein, Human, Recombinant (His) Human E. coli
NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the inter...
TMPH-01719 OPRM1 Protein, Human, Recombinant (His) Human in vitro E. coli expression system
Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to th...
TMPY-06411 GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)...
TMPY-05590 NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobuli...
TMPY-04273 FGFR2 Protein, Human, Recombinant (aa 1-378, His) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-05383 NKp30/NCR3 Protein, Human, Recombinant (hFc) Human HEK293
Natural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and...
TMPY-03969 SUSD4 Protein, Human, Recombinant (mFc) Human HEK293
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and ...
TMPY-04157 RANK/TNFRSF11A Protein, Human, Recombinant (His) Human HEK293
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-03883 CD47 Protein, Human, Recombinant (hFc) Human HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-01268 SMYD3 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger...
TMPY-01656 VEGF183 Protein, Human, Recombinant Human Baculovirus-Insect Cells
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPJ-00390 FGFR2IIIb Protein, Human, Recombinant (hFc) Human Human Cells
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPK-00447 CD45 Protein, Human, Recombinant (aa 26-577, hFc) Human HEK293
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPK-00399 FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPJ-00899 HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) Human Human Cells
Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belon...
TMPY-00276 PLGF/PGF Protein, Human, Recombinant (mFc) Human HEK293
PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 with mFc tag. The predicted molecular weight is 43.7 kDa. Accession number: P49763-3
TMPY-03960 COL9A1 Protein, Human, Recombinant (His) Human HEK293
COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 34.2 kDa. Accession number: P20849-3
TMPY-05514 RANK/TNFRSF11A Protein, Human, Recombinant (mFc) Human HEK293
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-03435 NCKIPSD Protein, Human, Recombinant (GST) Human E. coli
NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction and may function in the maintenance of sarcomeres and the assembly of myofibrils into sarcomeres. NCKIPSD also plays an importa...
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p38 gamma/MAPK12 Protein, Human, Recombinant
TMPY-04430
Species: Human
Expression System: Baculovirus-Insect Cells
p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)
TMPY-04429
Species: Human
Expression System: Baculovirus-Insect Cells
EphB2 Protein, Human, Recombinant (His & hFc)
TMPY-00784
Species: Human
Expression System: HEK293
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)
TMPY-04386
Species: Human
Expression System: Baculovirus-Insect Cells
EphB2 Protein, Human, Recombinant (His)
TMPY-01067
Species: Human
Expression System: HEK293
EPHB2 Protein, Cynomolgus, Recombinant (His)
TMPK-00563
Species: Cynomolgus
Expression System: HEK293
LGI1 Protein, Human, Recombinant (His & Myc)
TMPH-01609
Species: Human
Expression System: E. coli
MAPKAPK3 Protein, Human, Recombinant (GST)
TMPY-04378
Species: Human
Expression System: Baculovirus-Insect Cells
DUSP3 Protein, Human, Recombinant
TMPY-03482
Species: Human
Expression System: Baculovirus-Insect Cells
DUSP3 Protein, Human, Recombinant (His & GST)
TMPY-02127
Species: Human
Expression System: Baculovirus-Insect Cells
HNT/NTM Protein, Human, Recombinant (His)
TMPY-00357
Species: Human
Expression System: HEK293
FGF-8b Protein, Human, Recombinant
TMPY-06986
Species: Human
Expression System: E. coli
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
TMPY-04142
Species: Human
Expression System: HEK293
CD45 Protein, Human, Recombinant (aa 26-577, His)
TMPY-05748
Species: Human
Expression System: HEK293
Mesothelin Protein, Human, Recombinant
TMPY-00132
Species: Human
Expression System: HEK293
CD47 Protein, Human, Recombinant, Biotinylated
TMPY-05191
Species: Human
Expression System: HEK293
Neuropilin-2 Protein, Human, Recombinant (hFc)
TMPY-03763
Species: Human
Expression System: HEK293
Neuropilin-2 Protein, Human, Recombinant (His)
TMPY-00892
Species: Human
Expression System: HEK293
Periostin/OSF-2 Protein, Human, Recombinant (His)
TMPY-01020
Species: Human
Expression System: HEK293
CD47 Protein, Human, Recombinant
TMPY-04683
Species: Human
Expression System: HEK293
PRSS3 Protein, Human, Recombinant (His)
TMPY-01897
Species: Human
Expression System: HEK293
MST4 Protein, Human, Recombinant (GST)
TMPY-04374
Species: Human
Expression System: Baculovirus-Insect Cells
CDCP1 Protein, Human, Recombinant (His)
TMPY-04298
Species: Human
Expression System: HEK293
NCAM1 Protein, Human, Recombinant (His)
TMPY-00480
Species: Human
Expression System: HEK293
CD86 Protein, Human, Recombinant (His)
TMPY-01180
Species: Human
Expression System: HEK293
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
TMPJ-01099
Species: Human
Expression System: Human Cells
CD47 Protein, Human, Recombinant (aa 1-139, His)
TMPY-04935
Species: Human
Expression System: HEK293
GITR/TNFRSF18 Protein, Human, Recombinant (His)
TMPY-00072
Species: Human
Expression System: HEK293
STK40 Protein, Human, Recombinant (His & GST)
TMPY-04466
Species: Human
Expression System: Baculovirus-Insect Cells
ERK2 Protein, Mouse, Recombinant (His & GST)
TMPY-04571
Species: Mouse
Expression System: Baculovirus-Insect Cells
ERK2 Protein, Human, Recombinant (GST)
TMPY-04539
Species: Human
Expression System: Baculovirus-Insect Cells
NME1 Protein, Human, Recombinant (His)
TMPY-04467
Species: Human
Expression System: E. coli
OPRM1 Protein, Human, Recombinant (His)
TMPH-01719
Species: Human
Expression System: in vitro E. coli expression system
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06411
Species: Human
Expression System: HEK293
NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05590
Species: Human
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (aa 1-378, His)
TMPY-04273
Species: Human
Expression System: HEK293
NKp30/NCR3 Protein, Human, Recombinant (hFc)
TMPY-05383
Species: Human
Expression System: HEK293
SUSD4 Protein, Human, Recombinant (mFc)
TMPY-03969
Species: Human
Expression System: HEK293
RANK/TNFRSF11A Protein, Human, Recombinant (His)
TMPY-04157
Species: Human
Expression System: HEK293
CD47 Protein, Human, Recombinant (hFc)
TMPY-03883
Species: Human
Expression System: HEK293
SMYD3 Protein, Human, Recombinant (GST)
TMPY-01268
Species: Human
Expression System: Baculovirus-Insect Cells
VEGF183 Protein, Human, Recombinant
TMPY-01656
Species: Human
Expression System: Baculovirus-Insect Cells
FGFR2IIIb Protein, Human, Recombinant (hFc)
TMPJ-00390
Species: Human
Expression System: Human Cells
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
TMPK-00447
Species: Human
Expression System: HEK293
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
TMPK-00399
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)
TMPJ-00899
Species: Human
Expression System: Human Cells
PLGF/PGF Protein, Human, Recombinant (mFc)
TMPY-00276
Species: Human
Expression System: HEK293
COL9A1 Protein, Human, Recombinant (His)
TMPY-03960
Species: Human
Expression System: HEK293
RANK/TNFRSF11A Protein, Human, Recombinant (mFc)
TMPY-05514
Species: Human
Expression System: HEK293
NCKIPSD Protein, Human, Recombinant (GST)
TMPY-03435
Species: Human
Expression System: E. coli
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